TABLE 2

Absorbed Radiation Doses of 177Lu-PP-F11N in Tumors, Kidneys, Stomach, and Bone Marrow Without and With Coadministration of SG

Mean tumor dose (Gy/GBq)/patientMean kidney dose (Gy/GBq)/patientStomach dose (Gy/GBq)Bone marrow dose (Gy/GBq)Tumor-to-kidney dose ratioTumor-to-stomach dose ratioTumor-to-bone marrow dose ratio
PatientWithout SGWith SGWithout SGWith SGWithout SGWith SGWithout SGWith SGWithout SGWith SGWithout SGWith SGWithout SGWith SG
11.091.040.150.110.450.500.0220.0257.279.452.422.0849.641.6
23.591.420.130.070.380.470.0250.02827.620.39.453.02143.650.7
30.900.670.060.051.661.460.0280.03115.013.40.540.4632.121.6
40.850.640.080.100.200.180.0440.03910.66.44.253.5619.316.4
50.851.030.130.051.22.070.0360.0396.520.60.710.5023.626.4
60.630.630.050.050.130.260.0280.03312.612.64.852.4222.519.1
Median0.880.850.110.060.420.490.0280.03211.613.03.342.2527.924.0
IQR0.85–1.040.65–1.040.07–0.130.05–0.090.25–1.010.31–1.220.026–0.0340.025–0.0388.11–14.410.2–18.61.14–4.700.90–2.8719.3–45.216.4–37.8
Test for superiority(P)*0.380.380.690.221.00.160.22
  • * Two-sample paired sign test with significance level (α) of 0.05.