Pooled Analyses of PET Tracers
| Analysis | Studies (n) | Scans (n) | Sensitivity | Specificity | Positive LR | Negative LR |
| 18F-FDG | 12 | 171 | 84 (72–92) | 84 (69–93) | 5.29 (2.45–11.39) | 0.19 (0.10–0.36) |
| 18F-FET | 7 | 172 | 90 (81–95) | 85 (71–93) | 5.80 (2.89–11.66) | 0.12 (0.06–0.24) |
| 11C-MET | 8 | 151 | 93 (80–98) | 82 (68–91) | 5.12 (2.71–9.69) | 0.09 (0.03–0.26) |
| 18F-FDG (SA) | 6 | 121 | 82 (64–92) | 79 (61–90) | 3.95 (1.90–8.21) | 0.23 (0.10–0.51) |
| 18F-FET (SA) | 6 | 164 | 90 (80–96) | 86 (72–94) | 6.56 (3.02–14.21) | 0.11 (0.05–0.24) |
| 11C-MET (SA) | 6 | 135 | 91 (78–97) | 83 (68–92) | 5.32 (2.68–10.55) | 0.11 (0.04–0.28) |
LR = likelihood ratio; SA = sensitivity analysis without small studies.
Data in parentheses are 96% confidence intervals. Tracer abbreviations are shown in Supplemental Table 3.