Clinical Characteristics and PET Parameters Among Healthy Controls and Patients with MCI
| Characteristic | Control (n = 17) | MCI (n = 14) | P |
| Age (y) | 76.4 ± 6.2 | 80.5 ± 5.5 | 0.06 |
| Sex (male) | 9 (53%) | 7 (50%) | 0.88 |
| Race (African American; Caucasian; Asian) | 4 (24%); 12 (71%); 1 (6%) | 7 (50%); 7 (50%); 0 (0%) | 0.24 |
| Education (y) | 17.1 ± 3.3 | 15.7 ± 4.3 | 0.35 |
| Body mass index | 26.5 ± 3.0 | 26.7 ± 3.2 | 0.92 |
| Genetic vulnerability, APOE ε4 carrier (yes) | 3 (18%) | 5 (36%) | 0.28 |
| Cognitive performance | |||
| Sum-of-boxes CDR | 0.0 ± 0.1 | 1.1 ± 0.7 | <0.001 |
| CVLT short-delay free recall | 11.2 ± 2.9 | 7.9 ± 4.0 | 0.02 |
| CVLT long-delay free recall | 11.8 ± 2.7 | 7.6 ± 5.0 | 0.02 |
| PET parameters | |||
| Molar activity (GBq/μmol) | 3,878.1 ± 2,614.6 | 3,327.1 ± 2,133.8 | 0.52 |
| Injected dose of radioactivity (MBq) | 516.2 ± 22.2 | 517.2 ± 17.7 | 0.89 |
| Injected mass (μg) | 0.08 ± 0.06 | 0.11 ± 0.12 | 0.43 |
CVLT = California Verbal Learning Test.
P values are from comparison using Student t test or χ2 test as appropriate except for comparison of cognitive performance, which was assessed using analysis of covariance with age as covariate. Qualitative data are expressed as numbers followed by percentages in parentheses; continuous data are expressed as mean ± SD.