CATEGORY 1: Clinical Scenarios for BCR After Prior Definitive Treatment with RP or RT—Initial Imaging Investigation
| Scenario no. | Description | Appropriateness | Score |
| 1 | CT abdomen and pelvis with intravenous contrast | Appropriate | 8 |
| 2 | CT chest with intravenous contrast | Rarely appropriate | 2 |
| 3 | Bone scan (99mTc, 18F-NaF) | Appropriate | 8 |
| 4 | Pelvis MRI with and without intravenous contrast | Appropriate | 8 |
| 5 | 18F-FDG PET/CT (skull base to midthigh) | Rarely appropriate | 2 |
| 6 | 11C-choline PET/CT (skull base to midthigh) | May be appropriate | 6 |
| 7 | 18F-fluciclovine PET/CT (skull base to midthigh) | May be appropriate | 6 |
| 8 | 111In-capromab pendetide | Rarely appropriate | 1 |