Summary of Test Characteristics for Identifying CAV Grade 2 or 3
| Cutoff | Sensitivity | Specificity | PPV | NPV | +LR | −LR |
| MFR < 2.0 | 71.4% | 71.8% | 29.4% | 93.9% | 2.53 | 0.40 |
| MFR < 1.75 | 57.1% | 77.7% | 29.6% | 91.7% | 2.56 | 0.55 |
| Stress MBF < 3.7 | 92.9% | 22.4% | 16.5% | 95.0% | 1.20 | 0.32 |
| Stress MBF < 1.7 | 42.9% | 95.3% | 60.0% | 91.0% | 9.13 | 0.60 |
| SSS > 1 | 64.3% | 72.9% | 28.1% | 92.5% | 2.37 | 0.49 |
| SSS > 3 | 64.3% | 92.9% | 60.0% | 94.1% | 9.06 | 0.38 |
| LVEF ≤ 45 | 42.9% | 95.3% | 60.0% | 91.0% | 9.13 | 0.60 |
| MBF < 1.7 and SSS > 1 or LVEF ≤ 45 | 42.9% | 97.7% | 75.0% | 91.2% | 18.7 | 0.58 |
| SSS ≥ 4, LVEF ≤ 45 or MFR < 1.75 | 71.4% | 69.4% | 27.8% | 93.7% | 2.3 | 0.41 |
| LVEF ≤ 45% and MFR < 1.75* | 35.7% | 100.0% | 100.0% | 90.4% | > 99 | 0.64 |
PPV = positive predictive value; NPV = negative predictive value; LR = likelihood ratio; MFR = myocardial flow reserve; SSS = summed stress score; LVEF = left ventricular ejection fraction.