TABLE 1

Baseline Characteristics

CharacteristicData
Total patients (n)22 (100%)
Sex (n)
 Male11 (50%)
 Female11 (50%)
Mean age (y)
 All patients59 (range, 30–82)
 Female58 (range, 39–73)
 Male61 (range, 30–82)
ECOG status (n)
 016 (73%)
 16 (27%)
Time from diagnosis of uveal melanoma to liver metastases (mo)
 Mean34.9 (95%CI, 19.7–50.1)
 Median19 (range, 0–144)
Time from diagnosis of liver metastases to first SIRT (mo)
 Mean2.7 (95%CI, 2.3–3.1)
 Median3 (range, 1–5)
No. of patients with extrahepatic metastases before SIRT (n)4 (18%)
Liver tumor distribution (n)
 Whole liver20 (91%)
 Unilobar2 (9%)
Liver tumor volume (cm3)
 Mean318.1 (95%CI, 82.6–553.6)
 Median130 (range, 10–2,750)
Largest liver tumor (cm)
 Mean4.1 (95%CI, 2.4–5.8)
 Median2.6 (range, 1.4–18.6)
Number of liver metastases (n)
 0–1013 (59%)
 >119 (41%)
Tumor-to-liver uptake ratio*
 Mean4.0 (95%CI, 3.1–4.9)
 Median3.5 (range, 1–10)
SUVmax
 Mean7.5 (95%CI, 5.6–9.4)
 Median7.4 (range, 3.3–22.1)
  • * 99mTc-macroaggregated albumin SPECT/CT.