TABLE 4

Diagnostic and Prognostic Values of Previously Reported Thresholds

Diagnosis of CAV grade 2/3Annualized all-cause mortality rate
CutoffAbnormal (n)SensitivitySpecificityAbnormalNormal
MFR < 2.034 (34.3%)71.4%71.8%17.7%4.7%
MFR < 1.7527 (27.3%)57.1%77.7%19.6%5.2%
Stress MBF < 3.779 (79.8%)92.9%22.4%9.0%6.7%
Stress MBF < 1.710 (10.1%)42.9%95.3%35.8%7.0%
SSS > 132 (32.2%)64.3%72.9%12.3%7.0%
SSS > 315 (15.2%)64.3%92.9%18.7%7.1%
LVEF ≤ 4510 (10.1%)42.9%95.3%25.0%7.2%
MBF < 1.7 and SSS > 1 or LVEF ≤ 458 (8.1%)42.9%97.7%60.7%6.8%
SSS ≥ 4, LVEF ≤ 45 or MFR < 1.7536 (36.4%)71.4%69.4%15.4%5.0%
LVEF ≤ 45% and MFR < 1.75*5 (5.1%)35.7%100.0%51.6%7.4%
  • * Same patients would be identified using MBF < 1.7 and LVEF < 45%.

  • Uncorrected MFR was used because it was numerically superior in all models.