TABLE 2

Statistical Parametric Mapping of Increased mGluR5 Availability in Alcohol-Dependent Patients After 2 Months of Abstinence

Cluster level		Voxel level		Peak voxel MNI coordinate
K_ext	P	t	P	x	y	z	Anatomic area
11,805	<0.001^*	14.7	0.002^*	16	−12	−16	R parahippocampal gyrus
		13.8	0.004^*	14	−4	−12	R hippocampus
		13.4	0.004^*	−24	42	10	L middle frontal gyrus
		11.5	0.010^*	−18	−16	−16	L parahippocampal gyrus
		11.0	0.013^*	−14	−6	−12	L hippocampus
		10.6	0.015^*	−38	−14	26	L insula
		10.2	0.020^*	20	38	−14	R superior orbitofrontal gyrus
		9.2	0.035^*	−44	−12	24	L insula
		9.0	0.039^*	4	30	−4	R anterior cingulate cortex
		8.7	0.045^*	−28	−12	8	L putamen
		7.9	1.2⋅10⁻⁵	−2	0	26	L middle cingulum
		7.7	1.6⋅10⁻⁵	−32	−28	40	L postcentral gyrus
		7.7	1.6⋅10⁻⁵	34	10	28	R inferior frontal cortex
2,614	0.006^*	9.00	0.038^*	−48	−40	−10	L inferior temporal lobe
		6.53	5.4⋅10⁻⁵	−50	−24	−20	L inferior temporal lobe
		6.16	8.3⋅10⁻⁵	−38	−48	24	L angular gyrus