Toxicity Profiles of 73 Patients Treated with 225Ac-PSMA-617
| Toxic effect | Grade I or II | Grade III | Grade IV |
| Dry mouth | 62 (85) | 0 | 0 |
| Dry eyes | 4 (5) | 0 | 0 |
| Anorexia | 23 (32) | 0 | 0 |
| Nausea | 15 (21) | 0 | 0 |
| Vomiting | 4 (5) | 0 | 0 |
| Constipation | 19 (26) | 0 | 0 |
| Fatigue | 37 (51) | 0 | 0 |
| Weight loss | 28 (38) | 0 | 0 |
| Dyspepsia | 3 (4) | 0 | 0 |
| Dysgeusia | 4 (5) | 0 | 0 |
| Anemia | 22 (30) | 5 (7) | 0 |
| Leukopenia | 7 (10) | 2 (3) | 0 |
| Thrombocytopenia | 6 (8) | 1 (1) | 0 |
| Hypoalbuminemia | 14 (19) | 0 | 0 |
| Renal failure | 18 (25) | 3 (4) | 2 (3) |
| Dysuria | 13 (18) | 0 | 0 |
Data are reported as numbers of patients, with percentages of patients in parentheses.