TABLE 1

V_T and %Vol_roi Estimates

		ROI
Radioligand	Kinetic model	Centrum semiovale	Brain stem	Substantia nigra	Thalamus	Ventral striatum	Caudate	Putamen	Hippocampus	Insular cortex	Temporal lobe	Parietal lobe	Frontal cortex	Cerebellum
¹⁸F-BCPP-EF	1TC	10.8	16.2	19.2	21	29.6	19.2	31.9	19.6	24.9	23.1	24.5	23.3	28.5
		19%	17%	14%	21%	21%	32%	20%	19%	18%	18%	21%	19%	17%
	2TC	11.9	17.5	20.9	22.8	31.6	20.4	34.1	21.6	26.5	24.7	26	24.7	30.6
		17%	17%	14%	20%	20%	32%	18%	18%	17%	17%	20%	18%	16%
	MA1	11.9	17.5	20.9	22.9	31.6	20.4	34	21.7	26.6	24.8	26.1	24.8	30.6
		17%	17%	14%	20%	20%	32%	19%	18%	17%	17%	20%	19%	16%
¹¹C-SA-5403	1TC	23.2	31.7	30.5	28.6	34	22	37.4	32.5	39.4	35.7	33	34.6	41.7
		23%	18%	17%	21%	21%	31%	18%	16%	15%	16%	18%	23%	17%
	2TC	26.5	37.9	34	32.7	36.8	29.4	43.8	37.9	45.9	41.5	37.7	39.4	47.7
		31%	22%	17%	22%	19%	26%	17%	15%	16%	16%	19%	23%	19%
	MA1	29.1	36.5	34.6	31.9	37.9	25.1	42.1	37	44.6	40.4	36.7	38.4	46.5
		29%	20%	21%	21%	21%	28%	16%	14%	16%	16%	18%	23%	18%
¹¹C-UCB-J	1TC	5.7	7.2	8.5	11.2	20.9	12.4	20.9	13.4	20.5	17.6	15.5	14	15.9
		12%	12%	10%	16%	13%	28%	11%	13%	10%	10%	14%	14%	10%
	2TC	5.9	7.4	8.9	11.4	21.2	12.6	21.1	14.6	20.9	19.3	18	17.7	16.5
		11%	11%	10%	15%	12%	28%	11%	12%	9%	9%	14%	13%	9%
	MA1	5.8	7.4	8.8	11.5	21.2	12.6	21.1	14.6	20.9	19.3	18	17.7	16.5
		12%	11%	9%	15%	12%	28%	10%	13%	9%	9%	13%	13%	9%
%Vol_roi		0.11	2.33	0.07	1.38	0.15	0.46	0.62	0.50	0.83	8.00	6.28	5.39	6.49
		10%	5%	7%	5%	6%	11%	7%	9%	9%	6%	9%	9%	7%

Data are mean and COV.17 values for ¹¹C-SA-4503 2TC estimation; 3 values for ¹¹C-UCB-J 2TC estimation were excluded based on V_T of SE% > 10.