TABLE 4

PET Parameters Associated with PFS and OS in Log-Rank Cox Tests

PFSOS
ParameterHR4-y PFSPHR4-y OSP
Low MTV1 (ref)84% (79–89)0.0271 (ref)95% (92–98)0.0007
High MTV2.6 (1.1–6.0)67% (60–74)6.9 (2.1–21.9)66% (56–76)
Low Dmaxpatient1 (ref)88% (84–92)0.00031 (ref)93% (90–96)0.0095
High Dmaxpatient4.6 (1.9–11.2)55% (47–63)4.2 (1.3–13.1)69% (60–78)
Low Dmaxbulk1 (ref)86% (82–90)0.00031 (ref)91% (88–94)0.023
High Dmaxbulk4.1 (1.5–11.3)52% (42–62)3.3 (1–11.3)68% (57–79)
Low SPREADpatient1 (ref)85% (81–89)0.00111 (ref)86% (81–91)0.24
High SPREADpatient3.7 (1.3–10,1)52% (42–62)1.9 (0.5–6.8)78% (70–85)
Low SPREADbulk186% (82–90)<0.00011 (ref)90% (87–93)0.056
High SPREADbulk4.9 (1.7–13.9)45% (35–55)2.8 (0.8–9.9)69% (59–79)
Low no. of ROIs1 (ref)85% (81–89)0.00521 (ref)87% (82–92)0.21
High no. of ROIs3.1 (1.2–7.9)58% (49–67)1.9 (0.6–6.4)79% (72–86)
  • HR = hazard ratio.

  • Data in parentheses are 95% confidence intervals.