Multivariable Cox Regression Analysis for PFS and OS
| Parameter | aHR* | 95% CI | P |
| PFS | |||
| Best response | 3.29 | 1.54–7.01 | 0.002 |
| Compacity at T1 | 2.8 | 1.15–6.83 | 0.023 |
| Percent change of SUVpeak | 2.46 | 1.28–4.71 | 0.007 |
| Percent change of entropy GLCM | 2.54 | 1.08–6.00 | 0.033 |
| OS | |||
| Best response | 2.11 | 1.08–4.15 | 0.029 |
| CA 19-9 | 1.79 | 1.02–3.14 | 0.042 |
| SUVpeak at T1 | 3.31 | 1.37–8.00 | 0.008 |
| CoV at T2 | 2.02 | 1.03–3.94 | 0.04 |
↵* This backward-selected multivariable Cox regression model included age, sex, initial disease status, treatment, performance status by Eastern Cooperative Oncology Group, CA 19-9, best response, variables at T1 (skewness and compacity for PFS; SUVpeak and compacity for OS), T2 (SUVmax, CoV, entropy GLCM, and dissimilarity for PFS; SUVmax, TLG, CoV, entropy GLCM, and dissimilarity for OS), and, for PFS, percentage changes (SUVpeak, TLG, CoV, and entropy GLCM).
aHR = adjusted hazard ratio.