Variable | OR | P | ROC area | Se | Sp | LR+ | LR− |
Smooth lines | 2.26 (0.64–7.94) | 0.21 | 0.55 (0.46–0.64) | 0.90 (0.80–0.96) | 0.21 (0.07–0.42) | 1.13 (0.91–1.41) | 0.50 (0.18–1.43) |
Nodular lines | 1.69 (0.44–6.52) | 0.45 | 0.53 (0.45–0.62) | 0.19 (0.11–0.31) | 0.88 (0.68–0.97) | 1.55 (0.48–4.98) | 0.92 (0.76–1.12) |
Peribronchovascular thickening | 10.95 (3.33–36.0) | <0.001 | 0.76 (0.67–0.85) | 0.69 (0.56–0.79) | 0.83 (0.63–0.95) | 4.12 (1.66–10.2) | 0.38 (0.25–0.56) |
Subpleural space | 0.44 (0.09–2.15) | 0.31 | 0.47 (0.39–0.54) | 0.06 (0.02–0.15) | 0.88 (0.68–0.97) | 0.48 (0.12–1.98) | 1.07 (0.91–1.26) |
Satellite nodes | 0.65 (0.21–2.00) | 0.46 | 0.46 (0.36–0.56) | 0.18 (0.10–0.29) | 0.75 (0.53–0.90) | 0.72 (0.30–1.70) | 1.09 (0.85–1.41) |
Enlarged lymph nodes | 4.65 (1.68–12.8) | 0.003 | 0.68 (0.57–0.79) | 0.66 (0.53–0.77) | 0.71 (0.49–0.87) | 2.25 (1.18–4.3) | 0.48 (0.32–0.74) |
Pleural effusion | 1.09 (0.27–4.40) | 0.91 | 0.50 (0.43–0.58) | 0.13 (0.06–0.24) | 0.88 (0.68–0.97) | 1.07 (0.32–3.64) | 0.99 (0.83–1.18) |
Enlarged pulmonary veins | 0.32 (0.07–1.39) | 0.13 | 0.45 (0.37–0.53) | 0.06 (0.02–0.15) | 0.83 (0.63–0.95) | 0.36 (0.10–1.32) | 1.13 (0.93–1.36) |
Se = sensitivity; Sp = specificity; LR+ = positive likelihood ratio; LR− = negative likelihood ratio.
Data in parentheses are 95%CI. P < 0.003 was considered statistically significant to account for multiple testing.