TABLE 3

PET Imaging and CSF-Derived Biologic Clearance Half-Lives of 124I-Omburtamab from CSF

MeanMedian
ParameterTotal median25% Q50% Q75% QRange<5 y5–10 y>10 y<5 y5–10 y>10 y
124I-omburtamab PET
 Ventricle8.196.618.899.573.6–18.29.228.628.818.148.39.01
 Cervical6.866.369.088.893.9–16.98.139.729.546.786.659.7
 Thoracic7.836.7111.0110.395.0–25.09.1412.8410.827.517.949.87
 Lumbar7.026.329.8411.054.1–39.69.469.4614.916.626.9411.47
124I-omburtamab samples6.35.4910.3111.633.7–46.210.159.339.318.416.625.74
  • Q = quartile.

  • Data are in hours and exclude outliers 26 h and 44.4 h in single patient each.