TABLE 2

Summary of DAT Results

Region	PD vs. MSA-P	PD vs. PSP	PD vs. MSA-C	PD vs. CBS	MSA-P vs. PSP	MSA-P vs. MSA-C	PSP vs. CBS
Caudate	g = −0.39*	g = −1.08*	g = 0.73	g = −0.33	g = −0.37	g = 1.20	Insufficient data, n = 1/17
	CI = −0.77 to −0.01*	CI = −1.52 to −0.64*	CI = −1.18 to 2.63	CI = −1.08 to 0.43	CI = −1.13 to 0.39	CI = −0.20 to 2.59
	n = 10/609, I² = 63.2%*	n = 11/356, I² = 56.6%*	n = 2/92, I² = 0.0%	n = 3/122, I² = 0.0%	n = 5/114, I² = 47.7%	n = 3/99, I² = 45.6%
Putamen	g = −0.27	g = −0.86*	g = 1.51	g = 0.55	g = −0.47	g = 1.87*	Insufficient data, n = 1/17
	CI = −0.58 to 0.04	CI = −1.50 to −0.21*	CI = −0.57 to 3.59	CI = −0.42 to 1.53	CI = −1.22 to 0.28	CI = 0.46 to 3.29*
	n = 9/451, I² = 29.5%	n = 8/291, I² = 73.3%*	n = 2/92, I² = 0.0%	n = 3/122, I² = 26.8%	n = 4/101, I² = 27.5%	n = 3/99, I² = 34.1%*
Striatum	g = −0.34	g = −1.05*	Insufficient data, n = 1/55	g = 0.98	g = −0.70*	g = 1.46*	g = 1.30
	CI = −1.01 to 0.33	CI = −1.68 to −0.43*		CI = −0.65 to 2.62	CI = −1.21 to −0.19*	CI = 0.23 to 2.68*	CI = −5.49 to 8.09
	n = 4/255, I² = 46.6%	n = 9/390, I² = 73.3%*		n = 4/142, I² = 81.3%	n = 3/83, I² = 0.0%*	n = 4/133, I² = 63.5%*	n = 2/29, I² = 40.1%

CI = 95% confidence interval for g; n = number of studies or patients; I² = heterogeneity index.
There were no available studies that have compared MSA-C patients with PSP or CBS patients. There were also insufficient data for MSA-P vs. CBS comparison. Statistically significant comparisons are indicated with stars. Hemispheric values and ratios are presented in Supplemental Table 6.