TABLE 4

Radiation Dose Estimates to CSF for ¹³¹I-mAb-Omburtamab

Parameter	Mean	25% quartile	Median	75% quartile	Range
¹²⁴I-omburtamab PET-derived doses	0.620	0.436	0.523	0.755	0.21–2.948
Ventricle
Cervical	0.445	0.326	0.387	0.494	0.170–0.711
Thoracic	0.538	0.373	0.442	0.555	0.189–1.978
Lumbar	0.567	0.454	0.552	0.652	0.235–1.051
Whole CSF
From ¹²⁴I-omburtamab CSF samples	2.253	0.961	1.443	2.512	0.100–10.243
From ¹³¹I-omburtamab posttherapy CSF samples	1.534	0.695	1.1	1.841	0.041−8.386