Comparison of Patient and Tumor Characteristics of Training and Validation Cohorts
| Characteristic | Training (2003–2006) | Validation (2009–2012) | P |
| Age (y) | 59 (46–68) | 56.5 (45–74) | 0.698 |
| Injected activity (MBq) | 412.3 (336.6–473.5) | 371.0 (315.0–444.0) | 0.005* |
| GTV (cm3) | 114.7 (32.4–287.6) | 74.0 (23.0–257.0) | 0.027* |
| TMRmax | 2.47 (1.89–3.94) | 1.80 (1.27–3.46) | 0.0002* |
| rHV (%) | 15.3 (0–38.8) | 0.9 (0–26.5) | 0.0008* |
| MFMISO | 8.36 (7.19–14.77) | 8.01 (6.88–9.70) | 0.134 |
↵* P < 0.05.
rHV = relative hypoxic volume.
Data are median followed by range in parentheses.