Blood Markers at Baseline (HBS-Pre) and Follow-up (HBS-Post) and Their Correlation with Whole Liver Function
| Baseline | Follow-up | |||
| Blood marker | Data | ρ | Data | ρ |
| Bilirubin (μmol/L)* | 9 (5–31) | −0.73† | 10 (5–164) | −0.64† |
| Albumin (g/L) | 39.6 (30.2–46.1) | 0.63† | 38.7 (20.2–45.0) | 0.80† |
| AST (U/L) | 52 (22–313) | −0.68† | 51 (24–403) | −0.84† |
| ALT (U/L) | 45 (12–113) | −0.53 | 36 (8–232) | −0.73† |
| GGT (U/L) | 108 (66–386) | −0.26 | 204 (66–804) | 0.26 |
| ALP (U/L) | 142 (62–199) | −0.7† | 176 (73–347) | −0.19 |
| INR‡ | 1.03 (0.82–1.40) | −0.58† | 1.06 (0.84–1.74) | −0.51† |
| ALBI score* | −2.83 (−3.21 to −1.58) | −0.75† | −2.60 (−3.13 to −0.55) | −0.85† |
| Grade 1 | 10 (77%) | — | 6 (50%) | — |
| Grade 2 | 3 (23%) | — | 3 (25%) | — |
| Grade 3 | 0 (0%) | — | 3 (25%) | — |
↵* n = 12 (follow-up).
↵† P < 0.05.
↵‡ n = 12 (baseline and follow-up).
AST = aspartate aminotransferase; ALT = alanine aminotransferase; GGT = γ-glutamyltransferase; ALP = alkaline phosphatase; INR = international normalized ratio; ALBI = albumin–bilirubin.
Continuous data are median followed by range in parentheses. Categoric data are frequency followed by percentage in parentheses.