Biomarker class | Information provided (question answered) |
Diagnostic | Is the disease present? |
Phenotypic | What is the biologic behavior? |
Prognostic | What is the outcome? |
Predictive | Is the therapeutic target expressed? |
Intermediate endpoint | Does the disease respond to treatment? |
Pharmacokinetic | What is the drug distribution? |
Pharmacodynamic | Is the therapeutic target inhibited? |