TABLE 3

Current and Future Nuclear Theranostic Approaches

Nuclear theranostic pairTargetApplication
68Ga- and 177Lu-DOTATATESomatostatin receptorsNETs
68Ga- and 177Lu-PSMAPSMAProstate cancer
123I- and 131I-iobenguaneNorepinephrine reuptake transporterNeuroblastoma, paraganglioma, pheochromocytoma
68Ga- and 177Lu-FAPIFibroblast activation proteinMultiple cancers
68Ga- and 177Lu-3BP-227 NTR1 antagonistNeurotensin receptor 1Pancreatic cancer
124I- and 131I-girentuximabCarbonic anhydrase 9Renal cell cancer
123I- and 131I-iodineSodium/iodide symporterThyroid diseases
  • FAPi = fibroblast activation protein inhibitor.