TABLE 2

Tumor Uptake Rates of 177Lu-Labeled FAPI Derivatives and Calculated AUCs

Derivative1 h4 h6 h24 hAUC 1−24 h
FAPI-048.40 ± 0.369.44 ± 1.337.00 ± 1.202.86 ± 0.317,915
FAPI-219.35 ± 1.6212.38 ± 2.4212.77 ± 2.886.03 ± 0.6813,613
FAPI-356.68 ± 1.065.35 ± 1.135.29 ± 0.512.47 ± 0.235,902
FAPI-4612.35 ± 6.2510.60 ± 0.498.64 ± 0.522.29 ± 0.169,126
FAPI-559.30 ± 2.437.53 ± 2.137.37 ± 1.321.55 ± 0.167,289
  • Data are mean %ID/g ± SD (n = 3).