Radiolabeling of A2cDb Using 18F-TCO Click Chemistry
| 18F-DML-A2cDb | 18F-DMLsCy5-A2cDb | |||
| Parameter | Mean | SD | Mean | SD |
| D/P ratio | ND | 1.07 | 0.26 | |
| Labeling efficiency (%) | 77.1 | 17.7 | 52.7 | 18.6 |
| Specific activity (MBq/μg) | 0.41 | 0.12 | 0.50 | 0.30 |
| Radiochemical purity (%) | 97.3 | 1.6 | 89.1 | 10.6 |
| Immunoreactivity (%) | 42.9 | 8.7 | 41.5 | 6.9 |
| n | 3 | 3 | ||
ND = not determined.