Lesion-Based Outcome Parameters Corrected for Multiple Lesions Within Each Subject
Parameter | MRI | 95% CI | PET/MRI | 95% CI | P |
Sensitivity | 0.80 | 0.57–1.00 | 0.73 | 0.50–1-00 | 1.00 |
Specificity | 0.75 | 0.53–0.94 | 1.00 | 0.74–1.00 | 0.13 |
Accuracy | 0.77 | 0.65–0.90 | 0.87 | 0.73–1.00 | 0.53 |
CI = confidence interval.
Positive predictive value and negative predictive value (PPV/NPV) were 0.75/0.80 for MRI and 1.00/0.80 for PET/MRI. Interrater variability for PET/MRI was low, with Cohen κ of 0.86, and identical sensitivity, specificity, and accuracy were found for second reading.