TABLE 1

Clinical Questions for Potential Applications of Advanced Cardiac Imaging in Patients with Suspected or Established CS

Clinical questionClinical context
Diagnosis of CS in patients with established extracardiac sarcoidosisPositive initial screening: history, electrocardiogram, echocardiogram, or 24-h Holter monitoring
Diagnosis of CS in patients without established extracardiac sarcoidosisHigh degree of suspicion; examples include unexplained electrical abnormalities and unexplained cardiomyopathy
Initiation and monitoring of immunosuppressive therapyIdentification and quantification of inflammation, including longitudinal follow-up
Device therapy/implantable cardioverter-defibrillatorIdentification of high-risk patients for sudden cardiac death beyond traditional markers (left ventricular ejection fraction)