Changes in RT Protocol Due to CT and PET Information
| RT indication | ||||
| Parameter | All patients (n = 172) | PSA recurrence (n = 62) | PSA persistence (n = 88) | Definitive RT (n = 22) |
| Standard RT protocol | ||||
| Prostatic fossa/prostate | 112 (65%) | 57 (92%) | 44 (50%) | 11 (50%) |
| Prostatic fossa/prostate and lymphatic pathway | 60 (35%) | 5 (8%) | 44 (50%) | 11 (50%) |
| Change by CT information compared with standard RT target volume | ||||
| No change | 104 (60%) | 47 (76%) | 41 (47%) | 16 (73%) |
| Change | 68 (40%) | 15 (24%) | 47 (53%) | 6 (27%) |
| Individual changes* | ||||
| SIB local recurrence | 21 (12%) | 7 (11%) | 14 (16%) | 0 |
| SIB lymph node | 50 (29%) | 9 (15%) | 35 (40%) | 6 (27%) |
| SBRT bone | 8 (5%) | 0 | 8 (9%) | 0 |
| Change by PET/CT information compared with standard RT target volume | ||||
| No change | 65 (38%) | 31 (50%) | 20 (23%) | 14 (64%) |
| Change | 107 (62%) | 31 (50%) | 68 (77%) | 8 (36%) |
| Individual changes* | ||||
| SIB local recurrence | 45 (26%) | 17 (27%) | 28 (32%) | 0 |
| SIB lymph node | 76 (44%) | 14 (23%) | 54 (61%) | 8 (36%) |
| SBRT bone | 31 (18%) | 2 (3%) | 26 (30%) | 0 |
↵* Because multiple disease localizations are possible, individual changes in radiotherapy planning do not add up.
RT = radiotherapy; SIB = simultaneous integrated boost; SBRT = stereotactic body radiation therapy.