TABLE 1

Patient Characteristics

PatientPrimary tumor typemAb first/second administrationH-score of membrane stainingBest response*
1Breast cancer8 mg/24 mg35PD
2Head and neck cancer24 mg/1 mg/kg80ND
3Cervical cancer8 mg/30 mg/kg184PD
4Ovarian cancer8 mg/30 mg/kg195PD
5Prostate cancer8 mg/0.5 mg/kg200SD
6Colorectal cancer8 mg/—18ND
  • * First response evaluation was performed at 12 wk after treatment initiation to allow sufficient time for beneficial treatment effect that could be detected by RECIST 1.1.

  • Patient 6 was discovered to have brain metastasis as seen in baseline immuno-PET study and therefore was removed from further studies.

  • SD = stable disease; PD = progressive disease according to RECIST 1.1; ND = not determined.