TABLE 2

Tracer Uptake (SUVBW) in Different Tissues 60–120 Minutes After Injection (n = 3 Each)

TracerSCGSalivary glandLiverBloodBoneBackground
18F-DCFPyL20.9 ± 8.213.2 ± 5.378.4 ± 29.412.9 ± 3.010.5 ± 3.53.2 ± 0.7
18F-JK-PSMA-731.3 ± 10.514.4 ± 2.4119.3 ± 8.316.3 ± 4.29.9 ± 1.94.0 ± 1.0
18F-JK-PSMA-814.4 ± 2.69.0 ± 2.529.0 ± 7.28.6 ± 0.319.2 ± 2.13.2 ± 0.4
18F-PSMA-100794.8 ± 19.6*62.1 ± 14.2†50.7 ± 4.362.6 ± 10.7‖33.2 ± 9.5#15.9 ± 1.7**
68Ga-PSMA-1141.0 ± 3.438.4 ± 10.2‡43.7 ± 14.439.6 ± 4.6§18.5 ± 0.69.2 ± 0.6**

  • ↵* Significantly higher than any other (F4,10 = 26.52, P < 0.0001; post hoc P < 0.05).

  • ↵† Significantly higher than any other (F4,10 = 22.06, P < 0.0001; post hoc P < 0.05).

  • ↵‡ Significantly higher than 18F-DCFPyL (F4,10 = 22.06, P < 0.0001; post hoc P < 0.05).

  • ↵ Significantly higher than 18F-JK-PSMA-8 (18F-PSMA-1007 and 68Ga-PSMA-11. F4,10 = 7.83, P = 0.0040; post hoc P < 0.05).

  • ↵‖ Significantly higher than any other (F4,10 = 47.59, P < 0.0001; post hoc P < 0.05).

  • ↵§ Significantly higher than 18F-DCFPyL, 18F-JK-PSMA-7, and 18F-JK-PSMA-8 (F4,10 = 47.59, P < 0.0001; post hoc P < 0.05).

  • ↵# Significantly higher than any other (F4,10 = 12.19, P = 0.0007; post hoc P < 0.05).

  • ↵** Significantly different from all others (F4,10 = 93.81, P < 0.0001; post hoc P < 0.05).