TABLE 1

Patient and Tumor Characteristics

			Fluorescence assessment and potential benefit
			Tumor			Margins
Patient no.	Tumor site	Tumor stage	Fluorescent visualization^*	SBR^†	Detection of secondary lesion^‡	Successful presentation of peripheral margin^¶	Successful presentation of deep margin^§	Detection of residual disease^‖
1	Lateral tongue	pT2N0M0	Yes	1.92	—	+	+	—
2	Lateral tongue	pT3N2cM0	Yes	2.03	—	+	+	—
3	Retromolar trigone	pT3N0M0	Yes	2.38	—	—	—	—
4	Buccal mucosa	pT2N2bM0	Yes	2.68	+	+	+	—
5	Buccal mucosa	pT3N0M0	Yes	2.55	—	+	+	—
6	Hard palate	pT2N0M0	Yes	2.03	—	+	—	—
7	Lateral tongue	pT2N2bM0	Yes	1.77	—	+	+	—
8	Floor of mouth	pT3N2bM0	Yes	1.50	—	+	+	—
9	Retromolar trigone	pT4aN2bM0	Yes	1.56	—	—	—	—
10	Lateral tongue	pT2N0M0	Yes	2.34	—	+	+	—
11	Lateral tongue	pT1N0M0	NA	NA	—	+	+	—
12	Maxillary sinus	pT4N0M0	Yes	2.30	—	—	—	—
13	Scalp	NA	NA	NA	—	—	+	—
14	Primary unknown	pTxN3bM0	NA	NA	—	+	—	+

↵* Fluorescent visualization of primary tumor. Patients 11, 13, and 14 had no primary tumor.
↵† SBRs in patients 11, 13, and 14 could not be calculated in absence of primary tumor.
↵‡ Discovery of novel secondary primary tumors in the oral cavity.
↵¶ Fluorescent assessment of mucosal surface to screen close/positive margin (<5 mm).
↵§ Fluorescent assessment of deep surface to screen close/positive margin (<5 mm).
↵‖ Detection of residual disease to biopsy and correlate with pathologic findings.