Parameter | Tumor tattooing | Standard SN procedure | P |
Mean administered dose (MBq) ± SD | 100.0 ± 34.8 (median, 95.9) | 78.7 ± 7.3 (median, 79.0) | 0.059 |
Preoperative SN-related hot spots (n) | |||
Lymphoscintigraphy | 34 (median per patient, 2) | 50 (median per patient, 2) | 0.674 |
SPECT/CT | 34 (median per patient, 2) | 52 (median per patient, 3) | 0.836 |
Mean intraoperative SN results | |||
Fluorescent, in vivo | 4.0 (median, 3) | 2.7 (median, 2.5) | 0.192 |
Fluorescent, ex vivo | 3.8 (median, 3.5) | 3.2 (median, 3) | 0.365 |
Radioactive, in vivo | 2.9 (median, 3) | 2.7 (median, 2.5) | 0.745 |
Radioactive, ex vivo | 4.0 (median, 4) | 3.0 (median, 3) | 0.159 |
Total excised SNs (n) | 54 (mean, 4.5; median, 4) | 60 (mean, 3.2; median, 3) | 0.090 |
Total excised non-SNs (n) | 11 (mean, 0.9; median, 0.5) | 9 (mean, 0.5; median, 0) | 0.215 |
Total excised nodes (n) | 65 | 69 | |
Pathology (n) | |||
SNs | 84 | 83 | 0.072 |
Non-SNs | 32 | 7 | 0.306 |
Total nodes | 116 | 90 | 0.060 |
Tumor-positive SNs | 5 (in 3 patients) | 5 (in 4 patients) | |
Tumor-positive non-SNs | 1* (in 1 patient) | 0 | |
Tumor-positive nodes | 6 (in 3 patients) | 5 (in 4 patients) | |
Resection status (n) | |||
R0 | 11 (91.7%) | 19 (100.0%) | |
R1 | 1 (8.3%) | 0 |
↵* In this patient, 1 SN was also found tumor-positive.