TABLE 1

Preoperative, Intraoperative, and Pathologic Findings

ParameterTumor tattooingStandard SN procedureP
Mean administered dose (MBq) ± SD100.0 ± 34.8 (median, 95.9)78.7 ± 7.3 (median, 79.0)0.059
Preoperative SN-related hot spots (n)
 Lymphoscintigraphy34 (median per patient, 2)50 (median per patient, 2)0.674
 SPECT/CT34 (median per patient, 2)52 (median per patient, 3)0.836
Mean intraoperative SN results
 Fluorescent, in vivo4.0 (median, 3)2.7 (median, 2.5)0.192
 Fluorescent, ex vivo3.8 (median, 3.5)3.2 (median, 3)0.365
 Radioactive, in vivo2.9 (median, 3)2.7 (median, 2.5)0.745
 Radioactive, ex vivo4.0 (median, 4)3.0 (median, 3)0.159
Total excised SNs (n)54 (mean, 4.5; median, 4)60 (mean, 3.2; median, 3)0.090
Total excised non-SNs (n)11 (mean, 0.9; median, 0.5)9 (mean, 0.5; median, 0)0.215
Total excised nodes (n)6569
Pathology (n)
 SNs84830.072
 Non-SNs3270.306
 Total nodes116900.060
 Tumor-positive SNs5 (in 3 patients)5 (in 4 patients)
 Tumor-positive non-SNs1* (in 1 patient)0
 Tumor-positive nodes6 (in 3 patients)5 (in 4 patients)
Resection status (n)
 R011 (91.7%)19 (100.0%)
 R11 (8.3%)0
  • * In this patient, 1 SN was also found tumor-positive.