TABLE 3

AE Incidence Among 68 Patients with Unresectable Advanced PPGL Who Received Any Therapeutic Dose of HSA 131I-MIBG

AE by preferred termTreatment-related AE, all gradesTreatment-related AE, grades 3–5Any AE, all grades
Nausea52 (76)1 (1)53 (78)
Thrombocytopenia49 (72)28 (41)49 (72)
Anemia40 (59)14 (21)43 (63)
Leukopenia41 (60)28 (41)41 (60)
Fatigue32 (47)7 (10)41 (60)
Neutropenia39 (57)26 (38)39 (57)
Vomiting33 (49)1 (1)36 (53)
Dry mouth27 (40)028 (41)
Dizziness16 (24)1 (1)27 (40)
Headache15 (22)021 (31)
Hypotension8 (12)1 (1)18 (26)
Decreased appetite14 (21)1 (1)17 (25)
Diarrhea11 (16)2 (3)16 (24)
Constipation4 (6)1 (1)16 (24)
  • Data are numbers followed by percentages in parentheses.

  • Grade 1 = mild AE; grade 2 = moderate AE; grade 3 = severe AE; grade 4 = life-threatening or disabling AE; grade 5 = death related to AE.