Dosimetric Results for Hypothyroid PTC Patients with GFR ≥ Versus < 60 mL/min/1.73m2 in Comparison to rhTSH PTC Patients
| Parameters of iodine kinetics | Hypothyroid normal GFR (n = 227) | rhTSH (n = 60) | P | Hypothyroid low GFR (n = 20) | rhTSH (n = 60) | P |
| Activity (MBq) | 3,385 ± 634 | 3,274 ± 736 | 0.36 | 3,508 ± 512 | 3,274 ± 736 | 0.23 |
| Thyroid uptake (%) | 4.1 ± 1.8 | 3.7 ± 1.6 | 0.28 | 4.7 ± 1.5 | 3.7 ± 1.6 | 0.02 |
| Thyroid half-life (h) | 31.2 ± 15.5 | 30.3 ± 14.8 | 0.73 | 27.2 ± 8.3 | 30.3 ± 14.8 | 0.76 |
| Thyroid cumulated activity (MBq*d) | 277 ± 195 | 244 ± 174 | 0.14 | 311 ± 171 | 244 ± 174 | 0.06 |
| Thyroid residence time (h) | 2.0 ± 1.5 | 1.8 ± 1.2 | 0.37 | 2.1 ± 1.1 | 1.8 ± 1.2 | 0.16 |
| Thyroid dose (Gy) | 774 ± 548 | 685 ± 488 | 0.17 | 873 ± 481 | 685 ± 488 | 0.06 |
| Whole-body half-life (h) | 19.4 ± 8.0 | 16.5 ± 4.7 | ≤0.01 | 19.0 ± 4.5 | 16.5 ± 4.7 | 0.02 |
| Whole-body cumulated activity (MBq*d) | 1,619 ± 473 | 1,602 ± 508 | 0.89 | 2,325 ± 807 | 1,602 ± 508 | ≤0.01 |
| Whole-body residence time (h) | 11.6 ± 2.8 | 11.9 ± 3.5 | 0.88 | 15.7 ± 4.7 | 11.9 ± 3.5 | ≤0.01 |
| Remaining-body dose (mGy) | 86 ± 25 | 87 ± 28 | 0.94 | 127 ± 45 | 87 ± 28 | ≤0.01 |