TABLE 7

Literature Compilation of Dosimetric Studies Examining Iodine Kinetics in Hypothyroid and rhTSH Patients

First author and year of publicationTHW/rhTSH (n)Age THW/rhTSH (y)Latency OP-RIT (d)*THW TSH (mU/L)Body dose, half-life or residence timeThyroid dose, half-life or residence time
Menzel 2003 (6)163/6450/57≥28Ø∼50rhTSH < THW?
Sisson 2003 (7)87/1044/??Ø117rhTSH < THW?
Hänscheid 2006 (8)33/29?/??Ø84rhTSH < THWrhTSH > THW
Vaiano 2007 (9)29/1746/52≥28?rhTSH < THWrhTSH > THW
Remy 2008 (10)218/3648/44≥35Ø69rhTSH < THW?
Carvalho 2012 (12)50/5050/48≥56Ø59rhTSH < THW?
Ravichandran 2014 (13)81/22?/?≥35?rhTSH < THWrhTSH < THW
Grenfell 2015 (15)31/1949/4821 (median)?rhTSH = THW?
Guo 2015 (14)9/641/58≥28?rhTSH < THW?
Ravichandran 2016 (32)28/14?/?≥28Ø88rhTSH < THW?
Data presented in this publication281/6046/5118 (median)Ø51rhTSH = THWrhTSH = THW
  • * Or if not reported, time of L-T4 withdrawal.

  • THW = thyroid-hormone withdrawal; OP–RIT = time between surgery and radioiodine therapy (d).