TABLE 1

Demographics, MRI Measurements, and PET Values

ParameterData
Total cohort (n)190
 Women (n)113 (59.5%)
 Age (y)70.4 ± 7.56
 MMSE score29 ± 1.13
 Education (y)15.15 ± 4.42
 Global cortical atrophy score (0–3)0.79 ± 0.72
 Medial temporal atrophy score (0–4)0.65 ± 0.72
 Fazekas score (0–3)*1.18 ± 0.82
Quantitative cohort (n)185
 SUVr
  Mean ± SD1.33 ± 0.21
  Range0.79–2.13
 BPND
  Mean ± SD0.16 ± 0.12
  Range0.20–0.66
Concordant cohort (n)149
 PET-negative (n)130
  Global cortical atrophy score (0–3)0.74 ± 0.67
  Medial temporal atrophy score (0–4)0.57 ± 0.64
  Fazekas score (0–3)*1.18 ± 0.83
  SUVr
   Mean ± SD1.25 ± 0.09
   Range1.08–1.63
  BPND
   Mean ± SD0.12 ± 0.05
   Range0.02–0.27
 PET-positive (n)19
  Global cortical atrophy score (0–3)0.89 ± 0.81
  Medial temporal atrophy score (0–4)0.82 ± 0.75
  Fazekas score (0–3)*1.26 ± 0.87
  SUVr
   Mean ± SD1.83 ± 0.16§
   Range1.54–2.13
  BPND
   Mean ± SD0.43 ± 0.12§
   Range0.27–0.66

  • ↵* White matter hyperintensity (0 = 35; 1 = 101; 2 = 40; 3 = 14).

  • ↵§ P < 0.01, compared with PET-negative group.