TABLE 1

Characteristics of Groups With and Without Revascularization Within 90 Days After PET

Revascularization
Characteristic, # and % of groupYesSD or %NoSD or %P
Total (n = 3,774)1343.60%3,64096.40%
Age (y)66.2±9.962.0±11.9<0.00001
Body mass index28.5±4.228.0±4.40.173
Male, # and % of total11687%2,69474%0.001
Prior PCI, # and % of group7254%1,00328%<0.00001
Prior CABG, # and % of group2821%43712%0.002
MI in past 3 mo, # and % of group64%421%0.001
Past MI >3 mo, # and % of group2418%56015%0.427
Hypertension, # and % of group10377%2,43067%0.014
Dyslipidemia, # and % of group12896%3,25389%0.022
Diabetes, # and % of group3526%78422%0.206
Past or active smoking, # and %4131%143940%0.037
Medication, # and %
 Statin11586%2,57971%0.0001
 Antiplatelet11989%2,51069%<0.00001
 β-blocker9571%1,55643%<0.00001
 ACEI or ARB 8463%1,86651%0.009
 Calcium channel blocker2418%56716%0.465
 Diuretic4030%86824%0.110
Risk factors only—no history of CAD3627%2,10058%<0.00001
Known CAD (MI, angiography, revascularization), # and %9873%1,46340%<0.00001
Calcium > 120 HU on CT, # % of group13299%2,74875%
Recent typical angina, # and %5944%2627%<0.00001
Recent atypical angina, # % of group43%963%0.8055
Recent typical or atypical angina, # and %6347%35810%<0.00001
Angina with vasodilatory stress, # and %7254%2577%<0.00001
Stress ST depression > 1 mm, # and %1410%160%<0.00001
Stress EF by ECG gated PET, # and %61%12%70%10%<0.00001
Relative rest, % of LV < 60% of maximum – average7%±10%4%±10%0.001
Relative stress, % of LV < 60% of maximum – average28%±18%5%± 10%<0.00001
CFC severe, % of LV – average18%±21%2%±8%<0.00001
CFC severe, % of % LV – median12%0%
Mild CFC > 15% of LV, # and %11687%1,55643%<0.00001
Moderate CFC > 15% of LV, # and %3728%2226%<0.00001
Severe CFC > 0% of LV, # and %10881%61617%<0.00001
Minimum quadrant average CFR1.436±0.5922.39±0.69<0.00001
Minimum quadrant average stress flow (cc/min/g)0.968±0.4631.84±0.66<0.00001
Minimum quadrant CFR < 2.0, # and %10981%1,05529%<0.00001
Global average CFR1.91±0.632.60±0.70<0.00001
Global average stress flow (cc/min/g)1.36±0.502.05±0.66<0.00001
Stress flow maximum (cc/min/g)2.25±0.652.73±0.76<0.00001
CFR maximum3.20±0.983.65±1.00<0.00001
  • ACEI = angiotensin-converting enzyme inhibitors; ARB = angiotensin receptor blockers; EF = ejection fraction; HU = Hounsfield units.