Gastrin analog | Protease | Detected peptide sequences |
natLu-DOTA-MG11 | None | natLu-DOTA-dGlu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2 |
Neprilysin-1 | natLu-DOTA-dGlu-Ala-Tyr-Gly ↓ Trp-Met-Asp ↓ Phe-NH2 | |
Neprilysin-2 | natLu-DOTA-dGlu-Ala-Tyr-Gly ↓ Trp-Met-Asp-Phe-NH2 | |
Cathepsin-B | natLu-DOTA-dGlu-Ala-Tyr-Gly-Trp-Met-Asp ↓ Phe-NH2 | |
Cathepsin-C | natLu-DOTA-dGlu-Ala-Tyr-Gly-Trp-Met ↓ Asp-Phe-NH2 | |
Cathepsin-L | natLu-DOTA-dGlu-Ala-Tyr-Gly-Trp-Met ↓ Asp-Phe-NH2 | |
Cathepsin-S | natLu-DOTA-dGlu-Ala-Tyr-Gly-Trp-Met-Asp ↓ Phe-NH2 | |
natLu-DOTA-PP-F11 | None | natLu-DOTA-(dGlu)6-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2 |
Neprilysin-1 | natLu-DOTA-(dGlu)6-Ala-Tyr-Gly-Trp-Met-Asp ↓ Phe-NH2 | |
Cathepsin-L | natLu-DOTA-(dGlu)6-Ala-Tyr-Gly-Trp-Met ↓ Asp-Phe-NH2 | |
natLu-DOTA-PP-F11N | None | natLu-DOTA-(dGlu)6-Ala-Tyr-Gly-Trp-Nle-Asp-Phe-NH2 |
Cathepsin-L | natLu-DOTA-(dGlu)6-Ala-Tyr-Gly-Trp-Nle ↓ Asp-Phe-NH2 |
↓ = cleavage site identified by liquid chromatography/mass spectrometry.