TABLE 2

Comparison of Conventional and 68Ga-PSMA-11 PET/CT Imaging

CharacteristicConventional imaging68Ga-PSMA-11 PET/CTChangeP
Local relapse (n)
 PSA recurrence/persistence30/71 (42.3%)<0.001
  Total
  rcTx33/71 (46.5%)8/71 (11.3%)
  rcT033/71 (46.5%)53/71 (74.6%)
  rcT+5/71 (7.0%)10/71 (14.1%)
Lymph node spread (n)
 All patients15/121 (12.4%)39/121 (32.2%)25/121 (20.7%)*<0.001
 Initial diagnosis5/50 (10.0%)8/50 (16.0%)5/50 (10.0%)
  Intern iliac vessels2/50 (4.0%)
  Extern iliac vessels5/50 (10.0%)5/50 (10.0%)
  Presacral1/50 (2.0%)2/50 (4.0%)
  Obturatoric vessels2/50 (4.0%)
  Other1/50 (2.0%)
 PSA recurrence/persistence10/71 (14.1%)31/71 (43.7%)20/71 (28.2%)
  Intern iliac vessels3/71 (4.2%)10/71 (14.1%)
  Extern iliac vessels3/71 (4.2%)13/71 (18.3%)
  Presacral3/71 (4.2%)12/71 (16.9%)
  Obturatoric vessels2/71 (2.8%)*
  Other2/71 (2.8%)8/71 (11.3%)
Distant metastases (n)
 All patients26/121 (21.5%)41/121 (33.9%)23/121 (19.0%)*<0.001
 Initial diagnosis3/50 (6.0%)5/50 (10.0%)7/50 (14.0%)
  Lymph nodes2/50 (4.0%)3/50 (6.0%)
  Bone1/50 (2.0%)3/50 (6.0%)
  Other
 PSA recurrence/persistence23/71 (32.4%)36/71 (50.7%)16/71 (22.5%)
  Lymph nodes2/71 (2.8%)8/71 (11.3%)
  Bone18/71 (25.4%)27/71 (38.0%)
  Other3/71 (4.2%)3/71 (4.2%)
  • * Also, some patients with change in T staging.

  • Some patients with multiple forms of lymphatic/distant spread.