TABLE 1

Radionuclides Used for PRRT in Patients

IsotopeMain decay modeHalf-lifeTherapeutic particle and energyTissue penetration depthStatus
177Luβ, γ6.7 dβ, E(mean) = 0.149 MeV, E(max) = 0.497 MeVMean, 0.5 mm; maximum, 2 mmMA
90Yβ2.7 dβ, E(mean) = 0.937 MeV, E(max) = 2.284 MeVMean, 2.5 mm; maximum, 11 mmMA
111InEC2.8 dAuger e, 0.13–25.6 keV0.25 nm–13.6 μmMA
213Biα45.6 minα, 5.9/8.4 MeV85 μmCS
225Acα9.9 dα, 5.8–8.4 MeV47–85 μmCS
212Pbα, β, EC10.6 hα, 6.2–8.9 Mev50–100 μmCS
  • EC = electron capture; MA = marketing authorization; CS = clinical studies.