TABLE 1

Overview of Baseline Parameters of Different Treatment Groups of A549 Xenografts

ParameterRadiotherapyMetformin + radiotherapyControlP
Tumor volume (mm3)395 ± 57297 ± 51329 ± 650.5
Animal weight (g)29.6 ± 0.829.7 ± 0.929.4 ± 1.11.0
Baseline 18F-flortanidazole TBR3.60 ± 0.172.74 ± 0.263.47 ± 0.200.3
Δ18F-flortanidazole TBR (%)−13 ± 4−4 ± 4−14 ± 30.2
  • Δ18F-flortanidazole TBR = change in 18F-flortanidazole TBR after metformin.

  • Data are expressed as mean ± SEM.