TABLE 1

Patient Characteristics

CharacteristicAll patientsInitial diagnosisPSA persistence after surgeryPSA recurrence
No. of patients121501160
Median age (y)71 (50–84)72 (50–84)67 (53–75)69 (50–84)
Gleason score (n)
 ≤66 (5.0%)4 (8.0%)2 (3.3%)
 759 (48.8%)18 (36.0%)2 (18.2%)39 (65.0%)
 ≥855 (45.5%)28 (56.0%)9 (81.8%)18 (30.0%)
 Unknown1 (0.8%)1 (1.7%)
Median iPSA (ng/mL)9.95 (1.40–520.00)11.9 (3.50–313.13)18.58 (5.20–87.55)9.14 (1.40–520.00)
Nadir PSA (ng/mL)0.09 (<0.01–9.70)1.36 (0.53–9.70)0.07 (<0.01–3.00)
PSA at PET (ng/mL)3.06 (0.03–41.24)9.76 (0.06–37.10)1.27 (0.03–9.70)1.10 (0.10–41–24)
Risk group according  to D’Amico (n)
 Low3 (2.5%)3 (6.0%)
 Intermediate12 (9.9%)9 (18.0%)3 (5.0%)
 High106 (87.6%)38 (76.0%)11 (100.0%)57 (95.0%)
Ongoing ADT (n)
 Yes26 (21.5%)12 (24.0%)5 (45.5%)9 (15.0%)
 No95 (78.5%)38 (76.0%)6 (54.5%)51 (85.0%)
Prior RP only34 (28.1%)11 (100.0%)23 (38.3%)
Prior RT only5 (4.1%)5 (8.3%)
Prior RP and RT32 (26.4%)32 (53.3%)
Surgery margin
 R040 (33.1%)2 (18.2%)38 (69.1%)
 R124 (19.8%)9 (81.8%)15 (27.3%)
 Rx2 (1.7%)2 (3.6%)
  • iPSA = initial prostate-specific antigen serum level; ADT = androgen deprivation therapy; RP = radical prostatectomy; RT = radiotherapy.

  • Data in parentheses are ranges unless otherwise indicated.