Demographic and Clinical Characteristics of Study Subjects
| Characteristic | Community controls | Gene-negative controls | Pre-HD subjects |
| Subjects | 12 | 15 | 15 |
| Sex | |||
| Male | 6 | 9 | 8 |
| Female | 6 | 6 | 7 |
| Age (y) | 39.9 ± 15.1 | 37.0 ± 10.6 | 39.3 ± 9.9 |
| [CAG]n | NA | 20.33 ± 2.92 | 42.4 ± 1.8 |
| UHDRS motor | 0.7 ± 0.7 | 1.3 ± 1.1 | 2.3 ± 2.0 |
| Predicted age of onset (y) | — | — | 45.2 ± 4.8 |
| 10-y probability of disease onset (%) | — | — | 37.1 ± 28.1 |
| Disease burden* | 264.3 ± 74.6 |
↵* Calculated as ([CAG]n − 35.5) × age.
NA = not available; UHDRS = Unified HD Rating Scale.
Qualitative data are expressed as n; continuous data are expressed as mean ± SD.