Interobserver Agreement on Dichotomized DS, by Baseline Modality
I-PET/CT | EoT-PET/CT | |||||||
Agreement | Total (n = 465) | Baseline CT only (n = 108) | Baseline 18F-FDG PET or PET/CT (n = 357) | P* | Total (n = 457) | Baseline CT only (n = 114) | Baseline 18F-FDG PET or PET/CT (n = 343) | P* |
Positivity† | 23.3 | 18.5 | 24.8 | 17.5 | 18.0 | 17.3 | ||
Percentage OA | 87.7 (84.7–90.8) | 87.0 (80.2–93.8) | 88.0 (84.4–91.5) | 0.799 | 91.7 (89.0–94.3) | 93.9 (89.0–98.7) | 91.0 (87.8–94.1) | 0.332 |
Percentage PA | 73.7 (65.0–82.5) | 65.0 (41.6–88.4) | 75.7 (66.2–85.2) | 0.347 | 76.3 (66.3–86.2) | 82.9 (59.2–90.8) | 73.9 (62.0–85.9) | 0.486 |
Percentage NA | 92.0 (89.1–95.0) | 92.0 (85.8–98.3) | 92.0 (88.6–95.4) | 0.947 | 95.0 (92.6–97.3) | 96.3 (89.5–97.9) | 94.5 (91.7–97.4) | 0.605 |
DS 1–3 = negative; DS 4–5 = positive.
↵* P values of χ2 test refer to comparison of baseline CT vs. baseline PET or PET/CT.
↵† Prevalence of positive scans was calculated as sum of number of scans in which both reviewers scored positively and half of scans with discrepancies divided by total number of scans.
Data are percentages, with 95%CIs in parentheses.