Variable | No. of patients | No. of wearing-off events | Cumulative incidence | P |
Age at onset > 65 y + late H/M ratio > 1.78 | 46 | 1 | 2.2% | <0.001 |
Age at onset ≤ 65 y + late H/M ratio > 1.78 | 43 | 5 | 11.6% | |
Age at onset > 65 y + late H/M ratio ≤ 1.78 | 102 | 27 | 26.5% | |
Age at onset ≤ 65 y + late H/M ratio ≤ 1.78 | 75 | 38 | 50.7% | |
Total cohort | 266 | 71 | 26.7% |