Characteristics of the 1,068 Pediatric Patients with HL
| Skeletal involvement | ||||
| Yes | ||||
| Parameter | No | PET-only | BM or bone | P* |
| Total patients (n) | 929 | 44 | 95 | |
| Median age (y) | 14.9 | 15.3 | 14.9 | |
| Sex | ||||
| Male | 470 (51%) | 28 (64%) | 65 (68%) | <0.001 |
| Female | 459 (49%) | 16 (36%) | 30 (32%) | |
| B-symptoms (n) | 331 (36%) | 30 (68%) | 63 (66%) | <0.001 |
| Further extranodal involvement (n) | 289 (31%) | 18 (41%) | 50 (53%) | <0.001 |
| Bulky disease† (n) | 337 (37%) | 20 (45%) | 45 (47%) | 0.022 |