Participants Demographics
| Longitudinal data | ||||
| Variable | CU | MCI | ADD | Cross-sectional data, CU |
| No. of subjects | 421 | 116 | 40 | 1,349 |
| Mean age ± SD (y) | 77 ± 7 | 75 ± 9 | 69 ± 11 | 71 ± 10 |
| Age range (y) | 51–94 | 54–90 | 50–91 | 50–95 |
| Male (n) | 256 (61%) | 80 (69%) | 24 (60%) | 706 (52%) |
| Mean education ± SD (y) | 15 ± 3 | 15 ± 4 | 15 ± 2 | 15 ± 3 |
| Abnormal 11C-PiB (n) | 149 (35%) | 73 (63%) | 37 (92%) | 429 (32%) |
| Mean global GM 11C-PiB SUVR (crus, GM+WM, PVC) ± SD | 1.5 ± 0.34 | 1.8 ± 0.53 | 2.2 ± 0.41 | 1.43 ± 0.31 |
| APOE ε4 carrier (n) | 115 (27%) | 53 (46%) | 24 (60%) | 361 (27%) |
| Scans per person | ||||
| 1 | 1,349 (100%) | |||
| 2 | 300 (71%) | 79 (68%) | 26 (65%) | |
| 3 | 101 (24%) | 27 (23%) | 7 (18%) | |
| 4 | 17 (4%) | 5 (4%) | 5 (12%) | |
| 5 | 3 (1%) | 6 (5%) | 2 (5%) | |
| Mean time between first and last scan ± SD (y) | 2.8 ± 1.2 | 2.1 ± 1.1 | 1.9 ± 1.3 | |
crus = cerebellar crus1+crus2.