TABLE 4

Lung Dose Estimates in the 10 Patients with a LSF of 10% or More as Determined from Planar ^99mTc-MAA Imaging

							Lung dose^† (Gy)
	LSF (%)				⁹⁰Y activity (MBq)		Planar		SPECT/CT
Patient no.	Planar	SPECT/CT	Lung volume (L)	SIRT area	Resin	Glass	LSF	LSF and lung volume	LSF	LSF and lung volume
5	11.1	2.9	3.84	Right lobe	1.070	—	5.9	5.3	1.6	1.4
					—	3.600	19.9	17.7	5.2	4.6
6	12.0	3.8	1.80	Left lobe	730	—	4.4	8.1	1.4	2.6
					—	2.000^*	12.0	22.3	3.8	7.1
10	18.0	9.3	2.22	Whole liver	1.700	—	15.3	23.4	7.9	12.1
					—	5.000	45.0	68.8	23.2	35.5
18	32.3	13.5	2.41	Left lobe	820	—	13.2	18.4	5.6	7.7
					—	2.730^*	44.1	61.2	18.5	25.7
19	26.5	15.7	3.17	Whole liver	1.900	—	25.2	26.3	14.9	15.6
					—	6.920	91.7	95.9	54.2	56.6
21	11.7	4.4	2.98	Whole liver	1.820	—	10.6	12.7	4.0	4.8
					—	8.490	49.6	59.5	18.9	22.6
29	11.1	4.2	2.60	Whole liver	1.520	—	8.5	10.9	3.2	4.2
					—	4.480	25.0	32.2	9.5	12.3
30	11.3	4.3	4.52	Left lobe	900	—	5.1	3.8	1.9	1.4
					—	2.200^*	12.5	9.3	4.7	3.5
33	10.0	1.2	4.48	Left lobe	770	—	3.8	2.9	0.5	0.3
					—	2.070	10.3	7.7	1.2	0.9
34	14.5	7.4	3.02	Whole liver	1.850	—	13.4	14.9	6.8	7.6
					—	2.250	16.4	18.1	8.3	9.2

↵* Intended treatment with glass microspheres.
↵† Estimates based on LSF from planar imaging or SPECT/CT considering either standard lung mass (1,000 g) or individual lung volume as measured by CT and tissue density of 0.3 g/mL.