TABLE 1

Ventricular Function Data and Histologic Changes

ParameterControl (n = 7)CCC with normal perfusion (n = 17)CCC with MPD (n = 17)P
LVEF (%)81.9 ± 4.679.1 ± 1265.2 ± 19.2*0.012
WMSi1.0 ± 01.1 ± 0.31.4 ± 0.5†0.004
Inflammation (n/mm2)113.2 ± 38.8108.2 ± 53.6176.2 ± 86.8‡0.018
Fibrosis (%)4.5 ± 1.87.0 ± 3.18.0 ± 4.10.15

  • ↵* P < 0.05 vs. control and CCC animals with normal myocardial perfusion.

  • ↵† P < 0.05 vs. control animals.

  • ↵‡ P < 0.05 vs. CCC animals with normal myocardial perfusion.

  • Data are mean ± SD.