TABLE 1

Patient Characteristics

Patient characteristicValue*
Age (y)
 Median75.5
 Range57–85
Gleason score
 Median8
 No. of patients with   Gleason score of:
  <72
  76
  82
  96
  Unknown5
PSA (ng/mL)
 Median502
 Range6–1,855
Alkaline phosphatase (U/L)
 Mean166.8
 SD121.8
Localization of metastases
 Lymph node(s)9
 Bone21
 Liver1
 Lung5
 Brain1
 Other2
Local recurrence1
Previous therapy
 RPx10
 LRTx13
 CRPC21
 Abiraterone (Zytiga; Janssen Biotech, Inc.)17
 Enzalutamide (Xtandi; Astellas Pharma Inc.)12
 Zoledronic acid (Zometa; Novartis)/denosumab   (Xgeva; Amgen Inc.)8
223RaCl2 (Xofigo; Bayer)9
 CTx13
  • * Values are reported as numbers of patients unless otherwise indicated.

  • RPx = radical prostatectomy; LRTx = local radiation therapy; CRPC = castration-resistant prostate cancer; CTx = chemotherapy.