SUVR-1 and BPND in Baseline and Blocking Scans, and Percentage Reduction from Baseline in Pancreas and Brain Regions in NHPs with 11C-(+)-PHNO
| Antagonist | Measure | Pancreas | Substantia nigra | Putamen | Caudate |
| D3 | SUVR-1 | 2.8/1.2/57% | 2.8/0.3/89% | 4.7/4.1/13% | 3.7/2.9/22% |
| BPND | 1.5/0.8/46% | * | * | * | |
| D2 | SUVR-1 | 1.6/1.0/38% | 4.0/3.0/25% | 5.8/1.1/81% | 5.2/1.4/73% |
| BPND | 0.8/0.5/38% | * | * | * | |
| D2 | BPND | * | 3.5/2.7/23% | 4.3/0.9/79% | 4.3/0.9/79% |
↵* Dynamic data not available.
Data are presented as baseline values/blocking values/percentage reduction. BPND calculated using SRTM for pancreas (spleen reference) and SRTM2 for brain (cerebellum reference).