Correlation Between Tumor PET Imaging Parameters and Histologic–Biologic Characteristics of Breast Cancer
Parameter | SUV1max | SUV2max | ΔSUVmax | BF1 | BF2 | ΔBF |
SBR grade (I–II vs. III) | <0.001* | 0.002* | 0.040 | NS | NS | NS |
Body mass index (cutoff, 30) | NS | 0.023 | NS | 0.002* | 0.033 | NS |
Histologic type (ductal vs. lobular) | 0.041 | NS | NS | NS | NS | NS |
HER2 overexpression (yes vs. no) | NS | <0.001* | <0.001 | NS | <0.001* | <0.001* |
HR status (positive vs. negative) | <0.001* | 0.022 | 0.014 | NS | NS | NS |
↵* Statistically significant, using Bonferroni critical P value (multiple-comparisons corrections), calculated at 0.005.
SBR = Scarff–Bloom–Richardson grade; NS = not significant; HR = hormone receptor.
Data are P values obtained with Mann–Whitney test. Age, T stage, lymph node involvement, and menopausal status did not significantly correlate with tumor imaging characteristics.