All (n = 42) | OR (n = 14) | NR (n = 12) | |||||||
Metric | Mean | SD | Median | Range | Mean | SD | Mean | SD | OR vs. NR (P) |
Injected activity (GBq) | 1.18 | 0.43 | 1.10 | 0.29–2.60 | 1.07 | 0.51 | 1.18 | 0.29 | NS |
Lung shunt (%) | 6.8 | 4.0 | 5.9 | 1.73–18.6 | 6.4 | 4.0 | 6.5 | 3.0 | NS |
Tumor volume (cm3) | 407 | 462 | 213 | 8–2,043 | 214 | 175 | 385 | 374 | NS |
Mean dose (Gy) | |||||||||
Tumor | |||||||||
99mTc-MAA | 77 | 51 | 52 | 19–212 | 104 | 58 | 68 | 41 | 0.09 |
90Y-microspheres | 74 | 47 | 60 | 23–197 | 97 | 53 | 60 | 24 | 0.04 |
P | NS | NS | NS | ||||||
NTL | |||||||||
99mTc-MAA | 16 | 9 | 17 | 0–38 | 17 | 7 | 16 | 9 | NS |
90Y-microspheres | 22 | 9 | 21 | 7–44 | 24 | 8 | 21 | 10 | NS |
P | 0.003 | 0.02 | NS | ||||||
DVH indices | |||||||||
D50 (Gy) | |||||||||
99mTc-MAA | 61 | 49 | 43 | 9–219 | 92 | 62 | 50 | 27 | 0.04 |
90Y-microspheres | 66 | 46 | 48 | 15–200 | 87 | 49 | 50 | 21 | 0.02 |
P | NS | NS | NS | ||||||
D70 (Gy) | |||||||||
99mTc-MAA | 34 | 35 | 24 | 1–164 | 57 | 48 | 28 | 22 | 0.06 |
90Y-microspheres | 45 | 36 | 32 | 8–165 | 61 | 38 | 34 | 17 | 0.04 |
P | NS | NS | NS | ||||||
V120 (%) | |||||||||
99mTc-MAA | 19 | 23 | 8 | 0–83 | 33 | 27 | 13 | 16 | 0.04 |
90Y-microspheres | 19 | 25 | 8 | 0–87 | 28 | 28 | 9 | 13 | 0.05 |
P | NS | NS | NS |
↵* According to criteria of European Association for Study of Liver.
NS = not significant; D50 and D70 = minimum dose to 50% and 70%, respectively, of tumor volume; V120 = percentage of volume receiving at least 120 Gy.